Epithelial homeostasis refers to the balance and maintenance of epithelial cells within tissues and organs of the body. Epithelial cells form a protective barrier on the surface of organs and play important roles in functions such as absorption, secretion, and communication between cells. Research in epithelial homeostasis aims to understand the mechanisms that regulate the proliferation, differentiation, and survival of epithelial cells. This includes studying the signaling pathways, genetic regulation, and interactions with other cell types that contribute to maintaining the proper balance of epithelial cells in tissues. Imbalances in epithelial homeostasis can lead to diseases such as cancer, inflammatory conditions, and autoimmune disorders. Therefore, research in this area is important for developing therapies to target and treat these conditions by restoring proper epithelial cell function and balance.